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产品信息
PA5-53609
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639804
产品详细信息
Immunogen sequence: GIVRLRDGLR DRYPVEDYLD LFDLAAHQIH QGLQASSAKE QSKMNTIIIG EASASTMWDN NAWTFFYDNS TDGEPPFLTQ DFIHAFQPNA RLIVMLRDPV ER
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.
靶标信息
GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4, 6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; Carbohydrate sulfotransferase 15; DKFZp781H1369; GalNAc4S-6ST; hBRAG; MGC34346; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; RP11-47G11.1
基因别名: BRAG; CHST15; GALNAC4S-6ST; GALNAC4S6ST; KIAA0598
UniProt ID: (Human) Q7LFX5
Entrez Gene ID: (Human) 51363
