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产品信息
H00004435-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
6C1
抗原
CITED1 (NP_004134, 94 a.a. approximately 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: SMQLQKLNSQ YQGMAAATPG QPGEAGPLQN WDFGAQAGGA ESLSPSAGAQ SPAIIDSDPV DEEVLMSLVV ELGLDRANEL PELWLGQNEF DFTADFPSSC
靶标信息
This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cbp/p300-interacting transactivator 1; Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 1; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1; melanocyte-specific gene 1; Melanocyte-specific protein 1
基因别名: CITED1; MSG1
UniProt ID: (Human) Q99966
Entrez Gene ID: (Human) 4435
RNA polymerase II transcription coactivator activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
protein C-terminus binding
protein homodimerization activity
transcription regulatory region DNA binding
LBD domain binding
co-SMAD binding
transcription cofactor
embryonic axis specification
vasculogenesis
metanephros development
branching involved in ureteric bud morphogenesis
placenta development
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nucleocytoplasmic transport
apoptotic process
transforming growth factor beta receptor signaling pathway
brain development
cell proliferation
positive regulation of gene expression
negative regulation of Wnt signaling pathway
melanocyte differentiation
positive regulation of transforming growth factor beta receptor signaling pathway
response to lipopolysaccharide
response to insulin
response to cytokine
response to interferon-gamma
pigmentation
negative regulation of neuron apoptotic process
response to estrogen
negative regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to cAMP
mesenchymal to epithelial transition
SMAD protein signal transduction
labyrinthine layer development
spongiotrophoblast layer development
response to interleukin-1
response to interleukin-2
response to interleukin-4
response to interleukin-6
response to interleukin-9
response to interleukin-11
response to parathyroid hormone
response to transforming growth factor beta
