Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
CK1 delta Polyclonal Antibody
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 6
CK1 delta Antibody (PA5-18509) in ICC/IF
Immunofluorescence analysis of CK1 delta was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with CK1 delta Polyclonal Antibody (Product # PA5-18509) at 5 µg/mL in 0.1% BSA, incubated at 4 degree celsius ove... View More
产品信息
PA5-18509
产品规格
种属反应
Human,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (DREERLRHSRNPATR) corresponding to the internal amino acids of CSNK1D (aa 310-325).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10986846
产品详细信息
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for CK1 delta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: casein kinase 1; casein kinase 1, delta; Casein kinase I isoform delta; CK1d; CK1delta; CKI-delta; CKId; HGNC:2452; Tau-protein kinase CSNK1D
基因别名: 1200006A05Rik; AA409348; ASPS; CKIdelta; CSNK1D; D930010H05Rik; FASPS2; HCKID
UniProt ID: (Human) P48730, (Mouse) Q9DC28
Entrez Gene ID: (Human) 1453, (Mouse) 104318
glycoprotein binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
peptide binding
tau-protein kinase activity
phosphoprotein binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
G2/M transition of mitotic cell cycle
positive regulation of protein phosphorylation
DNA repair
rRNA processing
protein phosphorylation
endocytosis
microtubule nucleation
Golgi organization
signal transduction
regulation of cell shape
Wnt signaling pathway
peptidyl-serine phosphorylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
circadian regulation of gene expression
protein localization to Golgi apparatus
nonmotile primary cilium assembly
regulation of circadian rhythm
COPII vesicle coating
spindle assembly
protein localization to cilium
protein localization to centrosome
positive regulation of canonical Wnt signaling pathway
cell-cell adhesion
cellular response to nerve growth factor stimulus
positive regulation of non-canonical Wnt signaling pathway
phosphorylation
rhythmic process
