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产品信息
PA5-85245
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Casein Kinase 2 alpha.
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792388
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (84%), Xenopus laevis (86%), Rabbit (100%), Chicken (97%), Rhesus Monkey (100%), Bovine (100%).
Positive Control: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; protein kinase CK2
基因别名: CK2A1; CKII; CSNK2A1; CSNK2A3
UniProt ID: (Human) P68400
Entrez Gene ID: (Human) 1457
transcription, DNA-templated
regulation of transcription, DNA-templated
protein folding
protein phosphorylation
apoptotic process
signal transduction
positive regulation of cell proliferation
Wnt signaling pathway
positive regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of protein catabolic process
protein autophosphorylation
rhythmic process
regulation of catalytic activity
chaperone-mediated protein folding
mitotic spindle checkpoint
regulation of signal transduction by p53 class mediator
