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Immunogen sequence: MNNIHVENES LDNFLKETNK ENLLDILTEP ERKPDPKLYT RSKPKTDSYN QTKNSLVPKQ ALGKSSVNSA VLKDRVNKQF VGETQSRTFP VKSQQLSRGA DLARPGVKPS RTVPS
Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 53%.
The protein encoded by this gene is thought to be a mitotic spindle protein important to neural stem or progenitor cells. Mutations in this gene have been associated with spindle organization defects, including mitotic spindle defects, lagging chromosomes, and chromatin bridges. There is evidence that mutations in this gene are associated with Filippi syndrome, characterized by growth defects, microcephaly, intellectual disability, facial feature defects, and syndactyly. There is a pseudogene of this gene on chromosome 20. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cytoskeleton associated protein 2-like; Cytoskeleton-associated protein 2-like; FLJ40629; Radial fiber and mitotic spindle protein; Radmis
基因别名: CKAP2L
UniProt ID: (Human) Q8IYA6
Entrez Gene ID: (Human) 150468