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Bethyl Laboratories
CKII alpha Polyclonal Antibody
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Product Details
IHC-00036
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 300 and 350 of human Casein Kinase 2, alpha 1.
Conjugate
Form
Liquid
Concentration
0.50 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey and Gorilla
Target Information
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; protein kinase CK2
Gene Aliases: CK2A1; CKII; CSNK2A1; CSNK2A3
UniProt ID: (Human) P68400
Entrez Gene ID: (Human) 1457
transcription, DNA-templated
regulation of transcription, DNA-templated
protein folding
protein phosphorylation
apoptotic process
signal transduction
positive regulation of cell proliferation
Wnt signaling pathway
positive regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of protein catabolic process
protein autophosphorylation
rhythmic process
regulation of catalytic activity
chaperone-mediated protein folding
mitotic spindle checkpoint
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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