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产品信息
CL59467373100UL
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
1A11G10
偶联物
激发/发射光谱
593/614 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
靶标信息
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
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生物信息学
蛋白别名: ACC-alpha; ACC1; Acetyl-CoA carboxylase 1; Acetyl-Coenzyme A carboxylase alpha; EC 6.3.4.14; EC 6.4.1.2
基因别名: ACAC; ACACA; ACACAD; ACC; ACC1; ACCA
UniProt ID: (Human) Q13085
Entrez Gene ID: (Human) 31
tissue homeostasis
acetyl-CoA metabolic process
fatty acid biosynthetic process
biotin metabolic process
carnitine shuttle
positive regulation of cellular metabolic process
long-chain fatty-acyl-CoA biosynthetic process
multicellular organismal protein metabolic process
protein homotetramerization
lipid homeostasis
cellular response to prostaglandin E stimulus
malonyl-CoA biosynthetic process
