Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 4
CNR2 Antibody (PA5-18428) in WB
Western blot was performed using Anti-CNR2 Polyclonal Antibody (Product # PA5-18428) and a 40kDa band corresponding to CNR2 was observed across tissues tested except in Mouse Brain which is reported to be low expressing tissue for CNR2. Tissue extracts (30 µg lysate) of Mouse Spleen (Lane 1), Mouse Thymus (Lane 2), Mouse Brain (Lane 3), Mouse Ovary (Lane 4) were electrophoresed using NuPAGE™ 12% Bis-Tris Protein Gel (Product # NP0341BOX). Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # IB23001) by iBlot® 2... View More
产品信息
PA5-18428
应用
建议稀释比
已发表文章
产品规格
已发表种属
Hamster,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (TETEADGKITPWPD) corresponding to the C-terminus amino acids of CNR2 (aa 338-352).
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10984912
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
