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COL11A2 Antibody (MA5-27738) in ICC/IF
COL11A2 Monoclonal Antibody (GT473) detects COL11A2 protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: COL11A2 protein stained by COL11A2 Monoclonal Antibody (GT473) (Product # MA5-27738) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
MA5-27738
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
GT473
抗原
Recombinant protein encompassing a sequence within the N-terminus region of human COL11A2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2735152
产品详细信息
Positive Control: human COL11A2-transfected 293T cells (N-terminal fragment of COL11A2 isoform 1)
Predicted Reactivity: Mouse (85%), Rat (85%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Collagen alpha-2(XI) chain; collagen, type XI, alpha 2; DAQB-79P13.8; HGNC:2187; pro-a2 chain of collagen type XI; procollagen, type XI, alpha 2; type XI collagen alpha2 chain
基因别名: COL11A2; DFNA13; DFNB53; FBCG2; HKE5; PARP; STL3
UniProt ID: (Human) P13942, (Mouse) Q64739
Entrez Gene ID: (Human) 1302, (Mouse) 12815, (Rat) 294279
