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COL5A1 Antibody (PA5-109569) in WB
Western blot analysis of COL5A1 in Saos-2 cells. Samples were incubated with COL5A1 Polyclonal antibody (Product # PA5-109569) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-109569
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human COL5A1 (NP_0000843)
偶联物
形式
Liquid
浓度
1.77 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2854980
产品详细信息
Immunogen sequence: AKETTEVPEE LTPTPTEAAP MPETSEGAGK EEDVGIGDYD YVPSEDYYTP SPYDDLTYGE GEENPDQPTD PGAGAEIPTS TADTSNSSNP APPPGEGADD L
靶标信息
Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha1(V) collagen; Collagen alpha-1(V) chain; collagen, type V, alpha 1; pro-alpha1(V) collagen; procollagen type V alpha 1; procollagen, type V, alpha 1
基因别名: AI413331; COL5A1; EDSC
UniProt ID: (Human) P20908, (Mouse) O88207
Entrez Gene ID: (Human) 1289, (Mouse) 12831
blood vessel development
heart morphogenesis
cell adhesion
cell migration
extracellular matrix organization
collagen fibril organization
collagen catabolic process
collagen biosynthetic process
wound healing, spreading of epidermal cells
tendon development
extracellular fibril organization
skin development
integrin biosynthetic process
eye morphogenesis
regulation of cellular component organization
negative regulation of endodermal cell differentiation
