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产品信息
PA5-77244
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human COX10.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720971
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Defects in COX10 are a cause of mitochondrial complex IV deficiency (MT-C4D); also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase; cytochrome c oxidase assembly homolog 10; cytochrome c oxidase assembly protein; cytochrome c oxidase subunit X; heme A: farnesyltransferase; Heme O synthase; Protoheme IX farnesyltransferase, mitochondrial; similar to COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase
基因别名: 2410004F01Rik; AU042636; COX10
UniProt ID: (Human) Q12887, (Mouse) Q8CFY5
Entrez Gene ID: (Human) 1352, (Mouse) 70383, (Rat) 691853
cytochrome-c oxidase activity
farnesyltranstransferase activity
protoheme IX farnesyltransferase activity
prenyltransferase activity
protein geranylgeranyltransferase activity
protein prenyltransferase activity
4-hydroxybenzoate octaprenyltransferase activity
transferase activity
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity
cadaverine aminopropyltransferase activity
agmatine aminopropyltransferase activity
1,4-dihydroxy-2-naphthoate octaprenyltransferase activity
trans-pentaprenyltranstransferase activity
ATP dimethylallyltransferase activity
ADP dimethylallyltransferase activity
acyltransferase
mitochondrial fission
mitochondrial electron transport, cytochrome c to oxygen
heme biosynthetic process
heme a biosynthetic process
respiratory chain complex IV assembly
aerobic respiration
cellular respiration
heme O biosynthetic process
hydrogen ion transmembrane transport
mitochondrion organization
cytochrome complex assembly
protein farnesylation
