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Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLFPTSAQES SRGLPDANDL CLGLQSLSLT GWDRPWSTQD SDSSAQSSTH SVLSMLHNPL GNVLGKPPLS FLPLDPLGSD LVDKFPAPSV RGSRLDTRPI LDSRSSSPSD SDTSGFSSGS DHLSDLISSL RISPPLPFLS LSGGGPRDPL KMGVGSRMDQ EQAALAAVTP SPTSASKRWP GASVWPSWDL LEAPKDPFSI EREARLHRQA AAVNEATCTW SGQLPPRNYK NPIYSCKVFL GGVPWDITEA GLVNTFRVFG SLSVEWPGKD GKHPRCPPKG YVYLVFELEK SVRSLLQACS HDPLSPDGLS EYYFKMSSRR MRCKEVQVIP WVLADSNFVR SPSQRLDPSR TVFVGALHGM LNAEALAAIL NDLFGGVVYA GIDTDKHKYP IGSGRVTFNN QRSYLKAVSA AFVEIKTTKF TKKVQIDPYL EDSLCHICSS QPGPFFCRDQ VCFKYFCRSC WHWRHSMEGL RHHSPLMRNQ KNRDSS
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CEBP; CPE-binding protein 1; CPE-BP1; Cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; mCPEB-1; MGC34136; MGC60106
基因别名: AU024112; CPE-BP1; CPEB; CPEB-1; CPEB1; h-CPEB; hCPEB-1; mCPEB
UniProt ID: (Human) Q9BZB8, (Mouse) P70166
Entrez Gene ID: (Human) 64506, (Mouse) 12877