Invitrogen

CRF Polyclonal Antibody

2 篇参考文献

查看其他6个CRF抗体

抗体检测数据 (2)

CRF Antibody in Western Blot (WB)

CRF Antibody in Western Blot (WB)

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CRF Antibody (PA5-102356) in WB

Western blot analysis of CRF in various samples (Lane 1: HUVEC, Lane 2: 293). Samples were incubated with CRF polyclonal antibody (Product # PA5-102356).

CRF Antibody in Western Blot (WB)

CRF Antibody in Western Blot (WB)

Product Image Gallery

CRF Antibody in Western Blot (WB) — Western blot analysis of CRF in various samples (Lane 1: HUVEC, Lane 2: 293). Samples were incubated with CRF polyclonal antibody (Product # PA5-102356).

CRF Antibody in Western Blot (WB) — Western blot analysis of CRF in rat muscle. Samples were incubated with CRF polyclonal antibody (Product # PA5-102356).

产品信息

PA5-102356

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

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免疫组化（石蜡） (IHC (P))

1:50-1:200

-

免疫组化（冰冻） (IHC (F))

-

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Cat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human CRH(Accession P06850), corresponding to amino acid residues M1-P50.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2851763

产品详细信息

Antibody detects endogenous levels of total CRH.

靶标信息

Corticotropin Releasing Factor (CRF), a 41 amino acids neuropeptide, belongs to a family of structurally related peptides including urocortin, sauvagine and urotensin I. CRF is critical in the regulation of the pituitary-adrenal gland axis, and in endocrine, autonomic and behavioral responses to stress. CRF is widely distributed in the brain and peripheral nervous system with the highest levels in the hypothalamic paraventricular nucleus.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Corticotropin releasing hormone is present in the feline placenta and maternal serum.

Frontiers in endocrinology

Watt M,Mohammadzadeh P,Pinsinski E,Hollinshead FK,Bouma GJ

PA5-102356 was used in Western Blot to report for the first time the presence of CRH in feline placenta and maternal serum.

Tue May 02 00:00:00 EDT 2023

Corticotropin releasing hormone is present in the feline placenta and maternal serum.

Frontiers in endocrinology

Watt M,Mohammadzadeh P,Pinsinski E,Hollinshead FK,Bouma GJ

PA5-102356 was used in Western Blot to report for the first time the presence of CRH in feline placenta and maternal serum.

Tue May 02 00:00:00 EDT 2023

生物信息学

蛋白别名: Corticoliberin; corticotropin releasing factor; Corticotropin-releasing factor; Corticotropin-releasing hormone; CRF

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基因别名: CRF; CRH; CRH1; Gm1347

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UniProt ID: (Human) P06850, (Rat) P01143, (Mouse) Q8CIT0

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Entrez Gene ID: (Human) 1392, (Rat) 81648, (Mouse) 12918

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receptor binding hormone activity neuropeptide hormone activity protein binding corticotropin-releasing hormone activity corticotropin-releasing hormone receptor 1 binding corticotropin-releasing hormone receptor 2 binding peptide hormone

参与通路

positive regulation of protein phosphorylation synaptic transmission, dopaminergic glucocorticoid biosynthetic process inflammatory response signal transduction chemical synaptic transmission female pregnancy parturition learning or memory positive regulation of cell proliferation associative learning hormone-mediated apoptotic signaling pathway positive regulation of gene expression negative regulation of gene expression negative regulation of norepinephrine secretion positive regulation of circadian sleep/wake cycle, wakefulness positive regulation of cell death regulation of serotonin secretion diterpenoid metabolic process hypothalamus development lung development adrenal gland development positive regulation of cAMP biosynthetic process negative regulation of epinephrine secretion negative regulation of luteinizing hormone secretion locomotory exploration behavior positive regulation of insulin secretion involved in cellular response to glucose stimulus response to immobilization stress negative regulation of circadian sleep/wake cycle, REM sleep response to drug response to estrogen response to ethanol response to ether negative regulation of blood pressure response to pain ion homeostasis response to corticosterone positive regulation of corticotropin secretion positive regulation of cortisol secretion long-term synaptic potentiation positive regulation of digestive system process negative regulation of cell death negative regulation of glucagon secretion cellular response to cocaine cellular response to dexamethasone stimulus positive regulation of calcium ion import regulation of N-methyl-D-aspartate selective glutamate receptor activity positive regulation of corticosterone secretion positive regulation of behavioral fear response steroid metabolic process response to cocaine