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Immunogen sequence: ASAPPQDPAS SARNKRSHSG EPAPHIRAES HDMLMMMTYS MVPIRVMVDL CNSTKGICLT GP
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.
CRG-L2 is a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: collomin; colmedin; FLJ23917; Gliomedin
基因别名: CLOM; COLM; CRG-L2; CRGL2; GLDN; UNC-112; UNQ9339/PRO34011
UniProt ID: (Human) Q6ZMI3
Entrez Gene ID: (Human) 342035
分子生物学功能:
structural protein