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CRMP5 Antibody (PA5-109658) in WB
Western blot analysis of CRMP5 in extracts of various cell lines. Samples were incubated with CRMP5 Polyclonal antibody (Product # PA5-109658) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-109658
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 445-564 of human CRMP5/CRMP5/DPYSL5 (NP_0645192)
偶联物
形式
Liquid
浓度
0.42 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855069
产品详细信息
Immunogen sequence: VVYENGVFMC AEGTGKFCPL RSFPDTVYKK LVQREKTLKV RGVDRTPYLG DVAVVVHPGK KEMGTPLADT PTRPVTRHGG MRDLHESSFS LSGSQIDDHV PKRASARILA PPGGRSSGIW
靶标信息
The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Collapsin response mediator protein 5; CRMP-5; Dihydropyrimidinase-related protein 5; DRP-5; ULIP6 protein
基因别名: CRAM; CRMP-5; Crmp5; Dpysl5
UniProt ID: (Mouse) Q9EQF6
Entrez Gene ID: (Mouse) 65254
