Search Thermo Fisher Scientific
Antibody detects endogenous levels of total CROCC.
Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis (PubMed:27623382). Contributes to centrosome cohesion before mitosis (PubMed:16203858). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ciliary rootlet coiled-coil protein; CROCC; Rootletin; rootletin, ciliary rootlet protein; Tax1-binding protein 2
基因别名: CROCC; KIAA0445; ROLT
UniProt ID: (Human) Q5TZA2, (Mouse) Q8CJ40
Entrez Gene ID: (Human) 9696, (Mouse) 230872
分子生物学功能:
chromatin/chromatin-binding, or -regulatory protein