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CSGALNACT1 Antibody (PA5-66378) in ICC/IF
Immunofluorescent staining of CSGALNACT1 in human cell line U-2 OS shows localization to actin filaments. Samples were probed using a CSGALNACT1 Polyclonal Antibody (Product # PA5-66378).
产品信息
PA5-66378
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2664194
产品详细信息
Immunogen sequence: YMLACTPKGDE EQLALPRANS PTGKEGYQAV LQEWEEQHRN YVSSLKRQIA
Highest antigen sequence identity to the following orthologs - mouse 88%, rat 88%.
靶标信息
CSGALNACT1 transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). CSGALNACT1 required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. CSGALNACT1 is important role in chondroitin chain biosynthesis in cartilage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta4GalNAcT-1; Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; chondroitin beta1,4 N-acetylgalactosaminyltransferase; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; CsGalNAcT-1; glucuronylgalactosylproteoglycan 4-beta-N- acetylgalactosaminyltransferase
基因别名: beta4GalNAcT; CHGN; CSGalNAcT-1; CSGALNACT1; GALNACT1; UNQ656/PRO1287
UniProt ID: (Human) Q8TDX6
Entrez Gene ID: (Human) 55790
acetylgalactosaminyltransferase activity
peptidoglycan glycosyltransferase activity
glucuronosyltransferase activity
metal ion binding
glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
glycosyltransferase
endochondral ossification
nervous system development
cell recognition
cell proliferation
anatomical structure morphogenesis
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
UDP-N-acetylgalactosamine metabolic process
proteoglycan biosynthetic process
extracellular matrix organization
chondroitin sulfate biosynthetic process
heparin biosynthetic process
UDP-glucuronate metabolic process
chondroitin sulfate proteoglycan biosynthetic process
dermatan sulfate proteoglycan biosynthetic process
chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
cartilage development
