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Product Details
PA5-64471
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CSPG5. Recombinant protein control fragment (Product #RP-104262).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640203
Product Specific Information
Immunogen sequence: EEDDKDAVGG GDLEDENELL VPTGKPGLGP GTGQPTSRWH AVPPQHTLGS VPGSSIALRP RPGEPGRDLA SSE
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.
Target Information
Neuroglycan C is a transmembrane chondroitin sulfate proteoglycan that is exclusively expressed in the central nervous system. NGC gene expression is developmentally regulated being altered by addiction to psychostimulants and by nerve lesion. Its core protein has a particular multidomain structure differing from those of other known proteoglycans, and this protein is modified post-translationally in various ways such as phosphorylation and glycosylation. Neuroglycan C is a novel part-time proteoglycan that changes its structure from a proteoglycan form to a non-proteoglycan form without chondroitin sulfate chains during the development of the cerebellum and retina. Evidence suggests that Neuroglycan C is involved in neuronal circuit formation in the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acidic leucine-rich EGF-like domain-containing brain protein; Chondroitin sulfate proteoglycan 5; chondroitin sulfate proteoglycan 5 (neuroglycan C); MGC44034; Neuroglycan C
Gene Aliases: CALEB; CSPG5; NGC
UniProt ID: (Human) O95196
Entrez Gene ID: (Human) 10675
positive regulation of defense response to virus by host
nervous system development
cell differentiation
glycosaminoglycan metabolic process
chondroitin sulfate biosynthetic process
chondroitin sulfate catabolic process
dermatan sulfate biosynthetic process
regulation of growth
intracellular transport
modulation of synaptic transmission
mitophagy in response to mitochondrial depolarization
xenophagy
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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