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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alphaCstF-64 variant 4; betaCstF-64 variant 1; betaCstF-64 variant 2; betaCstF-64 variant 3; CF-1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit; Cleavage stimulation factor subunit 2; cleavage stimulation factor, 3' pre-RNA subunit 2, 64 kDa; cleavage stimulation factor, 3' pre-RNA, subunit 2; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa; CstF 64; CSTF 64 kDa subunit
基因别名: C630034J23Rik; CstF-64; CSTF2; Cstf64; mir-3112
UniProt ID: (Human) P33240, (Mouse) Q8BIQ5
Entrez Gene ID: (Human) 1478, (Rat) 683927, (Mouse) 108062
分子生物学功能:
mRNA polyadenylation factor