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Positive test controls include: Jurkat, HeLa, SW620, HepG2, Mouse thymus, Rat brain. The target is usually found in the following locations: Cytoplasm, Nucleus.
Immunogen sequence: EVLAILLQDN DENRELLGEL DGIDVLLQQL SVFKRHNPST AEEQEMMENL FDSLCSCLML SSNRERFLKG EGLQLMNLML REKKISRSSA LKVLDHAMIG PEGTDNCHKF VDILGLRTIF PLFMKSPRKI KKVGTTEKEH EEHVCSILAS LLRNLRGQQR TRLLNKFTEN DSEKVDRLME LHFKYLGAMQ VADKKIEGEK HDMVRRGEII DNDTEEEFYL RRLDAGLFVL QHICYIMAEI CNANVPQIRQ RVHQILNMRG SSIKIVRHII KEYAENIGDG RSPEFRENEQ KRILGLLENF
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. Diseases associated with CTNNBL1 include Immunodeficiency 99 With Hypogammaglobulinemia And Autoimmune Cytopenias.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: beta catenin-like 1; Beta-catenin-like protein 1; catenin, beta like 1; NAP; nuclear associated protein; nuclear protein NAP; Nuclear-associated protein; RP5-1118M15.1; Testis development protein NYD-SP19
基因别名: 5730471K09Rik; C20orf33; CTNNBL1; dJ633O20.1; NAP; NYD-SP19; P14L; PP8304
UniProt ID: (Human) Q8WYA6, (Mouse) Q80X64, (Rat) Q4V8K2
Entrez Gene ID: (Human) 56259, (Mouse) 66642, (Rat) 296320