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产品信息
PA5-53606
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human CTPS2. Recombinant protein control fragment (Product #RP-91884).
偶联物
形式
Liquid
浓度
0.30 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640232
产品详细信息
Immunogen sequence: GVCLGMQLAV IEFARNCLNL KDADSTEFRP NAPVPLVIDM PEHNPGNLGG TMRLGIRRTV FKTENSILRK LYGDVPFIEE RHRHRFEVNP NLIKQFEQND LSFVGQDVDG D^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
靶标信息
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CTP synthase 2; CTP synthase II; CTP synthetase 2; CTP synthetase type 2; cytidine 5'-triphosphate synthase 2; cytidine 5'-triphosphate synthetase 2; cytidine triphosphate synthase II; UTP--ammonia ligase 2; UTP-ammonia ligase 2
基因别名: CTPS2
UniProt ID: (Human) Q9NRF8, (Rat) Q5U2N0
Entrez Gene ID: (Human) 56474, (Rat) 619580
