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CTR1 Antibody (PA1-16586) in IHC (P)
Immunohistochemical analysis of CTR1 in breast cancer tissue. Samples were incubated in CTR1 polyclonal antibody (Product # PA1-16586). Panel 1: human CTR1 staining of breast cancer tissue. Panel 2: human CTR1-antigen competition in breast cancer tissue.
产品信息
PA1-16586
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Human,
Mouse,
Pig,
Rat,
Xenopus,
Zebrafish
已发表种属
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide of C-terminal region of human CTR1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_568506
产品详细信息
Suggested positive control: human breast cancer and kidney tissue.
靶标信息
The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: copper transport 1 homolog; Copper transporter 1; Copper uptake transporter 1; CTR1; hCTR1; high affinity copper uptake protein; High affinity copper uptake protein 1; high-affinity copper uptake protein; Liver regeneration-related protein LRRGT00200; rCTR1; solute carrier family 13 (sodium/sulphate symporters), member 1; solute carrier family 31 (copper transporter), member 1; solute carrier family 31 (copper transporters), member 1; Solute carrier family 31 member 1
基因别名: 4930445G01Rik; AI787263; AU016967; COPT1; ctr-1; CTR1; LRRGT00200; SLC31A1; Xctr1; XELAEV_18038194mg; zgc:76839
UniProt ID: (Human) O15431, (Pig) Q8WNR0, (Rat) Q9JK41, (Mouse) Q8K211
Entrez Gene ID: (Human) 1317, (Pig) 397186, (Dog) 481678, (Rat) 171135, (Mouse) 20529, (Zebrafish) 403028, (Xenopus) 379422
copper ion transport
drug transmembrane transport
cellular copper ion homeostasis
copper ion transmembrane transport
cellular response to cisplatin
copper ion import into cell
copper ion import
transport
ion transport
hypotonic salinity response
response to copper ion
cellular response to estrogen stimulus
