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产品信息
H00001512-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CTSH (AAH02479, 1 a.a. approximately 335 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MWATLPLLCA GAWLLGVPVC GAAELSVNSL EKFHFKSWMS KHRKTYSTEE YHHRLQTFAS NWRKINAHNN GNHTFKMALN QFSDMSFAEI KHKYLWSEPQ NCSATKSNYL RGTGPYPPSV DWRKKGNFVS PVKNQGACGS CWTFSTTGAL ESAIAIATGK MLSLAEQQLV DCAQDFNNHG CQGGLPSQAF EYILYNKGIM GEDTYPYQGK DGYCKFQPGK AIGFVKDVAN ITIYDEEAMV EAVALYNPVS FAFEVTQDFM MYRTGIYSST SCHKTPDKVN HAVLAVGYGE KNGIPYWIVK NSWGPQWGMN GYFLIERGKN MCGLAACASY PIPLV
靶标信息
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.
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生物信息学
蛋白别名: aleurain; CATH; cathepsin B3; cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase; Pro-cathepsin H
基因别名: ACC-4; ACC-5; ACC4; ACC5; CPSB; CTSH
UniProt ID: (Human) P09668
Entrez Gene ID: (Human) 1512
endopeptidase activity
aminopeptidase activity
cysteine-type endopeptidase activity
serine-type endopeptidase activity
protein binding
peptidase activity
cysteine-type peptidase activity
cysteine-type endopeptidase activator activity involved in apoptotic process
HLA-A specific activating MHC class I receptor activity
thyroid hormone binding
cysteine protease
metanephros development
T cell mediated cytotoxicity
adaptive immune response
immune response-regulating signaling pathway
proteolysis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of epithelial cell migration
neuropeptide catabolic process
bradykinin catabolic process
positive regulation of peptidase activity
antigen processing and presentation
positive regulation of cell migration
zymogen activation
protein destabilization
response to retinoic acid
membrane protein proteolysis
negative regulation of apoptotic process
surfactant homeostasis
cellular protein metabolic process
positive regulation of angiogenesis
proteolysis involved in cellular protein catabolic process
dichotomous subdivision of terminal units involved in lung branching
ERK1 and ERK2 cascade
cellular response to thyroid hormone stimulus
positive regulation of apoptotic signaling pathway
