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产品信息
MA1-24668
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
42705.111
抗原
Human CXCR1 transfected NSO mouse myeloma cells.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
purified
保存液
PBS with 5% trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_779600
产品详细信息
Recommended positive controls: human spleen.
Human CXCR1 reacts with CXCR1 transfected cells and not with the parent cell line by flow cytometry. Thw antibody shows no cross-reactivity with human CXCR2.
Endotoxin level is less than 10 ng per mg antibody as determined by the LAL method.
靶标信息
CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 1; CC motif chemokine; CCmotif chemokine; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CXC; CXC motif chemokine; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL-RA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
基因别名: C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; CXCR1; IL8R1; IL8RA; IL8RBA
UniProt ID: (Human) P25024
Entrez Gene ID: (Human) 3577
