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Quantity: 100 µg IgG per vial
CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 2; CC motif chemokine; CCmotif chemokine; CD182; CD182 antigen; chemokine (C-X-C) receptor 2; CXC; CXC motif chemokine; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8 receptor alpha chain; Il-8 receptor b; IL-8 receptor beta; IL-8R B; interleukin 8 receptor, beta; interleukin-8 receptor type B
基因别名: CD128; CDw128; Cmkar2; Cxcr2; Gpcr16; IL-8rb; IL-8Rh; IL8RA; Il8rb; mIL-8RH
UniProt ID: (Mouse) P35343, (Rat) P35407
Entrez Gene ID: (Mouse) 12765, (Rat) 29385