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产品信息
PA5-75653
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human CYBA.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719381
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
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生物信息学
蛋白别名: cytochrome b light chain; Cytochrome b(558) alpha chain; cytochrome b(558) alpha-subunit; cytochrome b, alpha polypeptide; Cytochrome b-245 light chain; cytochrome b-245, alpha polypeptide; cytochrome b558 alpha-subunit; Cytochrome b558 subunit alpha; cytochrome beta-558; flavocytochrome b-558 alpha polypeptide; Neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; p22 phox; p22-phox; p22phox; Superoxide-generating NADPH oxidase light chain subunit
基因别名: b558; CYBA; nmf333; p22-PHOX; p22phox
UniProt ID: (Human) P13498, (Mouse) Q61462, (Rat) Q62737
Entrez Gene ID: (Human) 1535, (Mouse) 13057, (Rat) 79129
positive regulation of endothelial cell proliferation
negative regulation of glomerular filtration by angiotensin
superoxide metabolic process
transport
inflammatory response
regulation of blood pressure
smooth muscle hypertrophy
cytochrome complex assembly
positive regulation of cell growth
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of superoxide anion generation
positive regulation of toll-like receptor 2 signaling pathway
superoxide anion generation
innate immune response
respiratory burst
positive regulation of smooth muscle cell proliferation
hydrogen peroxide biosynthetic process
positive regulation of phagocytosis
regulation of release of sequestered calcium ion into cytosol
oxidation-reduction process
positive regulation of mucus secretion
cellular response to organic substance
reactive oxygen species metabolic process
positive regulation of defense response to bacterium
positive regulation of reactive oxygen species biosynthetic process
response to reactive oxygen species
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
response to nutrient levels
response to drug
cell redox homeostasis
vascular endothelial growth factor receptor signaling pathway
response to interleukin-1
cellular response to amino acid stimulus
cellular response to mechanical stimulus
cellular response to glucose stimulus
cellular response to tumor necrosis factor
cellular response to organic cyclic compound
cellular response to gamma radiation
