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产品信息
PA5-75328
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 290-336 of Human CysLTR2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719056
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CysLT(2); CysLT-2; CysLTR2; cysteinyl leukotriene CysLT2 receptor; Cysteinyl leukotriene receptor 2; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; hGPCR21; HPN321; RSBPT32
基因别名: 2300001H05Rik; Cltr2; CYSLT2; CYSLT2R; CYSLTR2; GPCR21; HG57; hGPCR21; HPN321; KPG_011; PSEC0146
UniProt ID: (Human) Q9NS75, (Rat) Q924T9, (Mouse) Q920A1
Entrez Gene ID: (Human) 57105, (Rat) 170926, (Mouse) 70086
immune response
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
positive regulation of cell death
positive regulation of angiogenesis
leukotriene signaling pathway
positive regulation of ERK1 and ERK2 cascade
G-protein coupled receptor signaling pathway
signal transduction
