Invitrogen

CaMKII beta/gamma Polyclonal Antibody

CaMKII beta/gamma Antibody in Western Blot (WB)

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CaMKII beta/gamma Antibody (PA5-36195) in WB

Western blot analysis of CaMKII beta/gamma in Lane 1: U-87MG whole cell lysate (40 µg), Lane 2: PC3 whole cell lysate (40 µg), Lane 3: A549 whole cell lysate (40 µg), Lane 4: H9C2 whole cell lysate (40 µg), Lane 5: CT26 whole cell lysate (40 µg). Samples were incubated with CaMKII beta/gamma polyclonal antibody (Product # PA5-36195) at a dilution of 1:500.

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产品信息

PA5-36195

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化 (IHC)

1:50-1:200

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免疫细胞化学 (ICC/IF)

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to amino acids 601-652of human CaMKII beta

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2553410

产品详细信息

This antibody detects endogenous protein at a molecular weight of 50-80 kDa.

Purity is >95% by SDS-PAGE.

靶标信息

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.

Cell reports

Wiederstein JL,Nolte H,Günther S,Piller T,Baraldo M,Kostin S,Bloch W,Schindler N,Sandri M,Blaauw B,Braun T,Hölper S,Krüger M

PA5-36195 was used in Immunohistochemistry-immunofluorescence to conclude that the methyltransferase METTL21C is an important modulator of protein degradation in skeletal muscle under both normal and enhanced protein breakdown conditions.

Tue May 01 00:00:00 EDT 2018

生物信息学

蛋白别名: Ca++/calmodulin-dependent protein kinase II beta subunit; Ca2+/calmodulin-dependent protein kinase II; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II gamma chain; Calcium/calmodulin-dependent protein kinase type II subunit beta; Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II beta subunit; CaM kinase II subunit beta; CaM kinase II subunit gamma; CaM-kinase II beta chain; caM-kinase II gamma chain; CaMK II; caMK-II subunit beta; caMK-II subunit gamma; proline rich calmodulin-dependent protein kinase

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基因别名: CAM2; CAMK; CAMK-II; CAMK2; CAMK2B; Camk2d; CAMK2G; CAMKB; CAMKG; Ck2b