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Calretinin Antibody (18-0211) in ICC/IF
Frontiers in cell and developmental biology 2022 -
FIGURE 3 Ednrb -/- mice lack a GABA-ergic neuron population marked by Neurod6 and Gad2 in the SI of WT mice. (A) Violin plots showing expression of the denoted GABA-ergic neuron marker genes in WT and Ednrb -/- SI. (B) Gross appearance of the stomach and SI of WT and Ednrb -/- mice. (C) , (D) High-power microscopy images showing immunostaining for the denoted proteins in the SI of WT and Ednrb -/- mice, as ... View More
产品信息
18-0211
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
克隆号
DC8
抗原
Recombinant human calretinin
偶联物
Unconjugated
形式
Liquid
纯化类型
purified
保存液
PBS with 1% BSA
内含物
0.1% sodium azide
保存条件
2-8°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2925239
产品详细信息
Calretinin, a calcium-binding protein with a molecular weight of 29 kD, is a member of the large family of EF-hand proteins that also includes S-100 protein. This antibody is useful for differentiating mesotheliomas from adenocarcinomas. Positive tissue: Human normal pleura lining/ malignant mesothelioma.
Expected Staining Pattern: Cytoplasmic and nuclear
靶标信息
Calretinin is encoded by the CALB2 gene located on chromosome 16. It is a troponin C superfamily protein having six EF-hand structural motifs. The EF motif allows the protein to bind calcium, and function in calcium signaling, calcium buffering, and modulating neuronal excitability. Calretinin is expressed in the mesothelium, mast cells, some neural cells, hair follicles, and fat cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 29 kDa calbindin; 29kD calretinin; 29kDa calbindin; calbindin 2, (29kD, calretinin); calbindin D29K; Calretinin; CR; testicular secretory protein Li 8
基因别名: CAB29; CAL2; CALB2; CR
UniProt ID: (Human) P22676
Entrez Gene ID: (Human) 794
