Invitrogen

Cannabinoid Receptor 1 Polyclonal Antibody

查看其他21个Cannabinoid Receptor 1抗体

抗体检测数据 (1)

Cannabinoid Receptor 1 Antibody in Western Blot (WB)

Cannabinoid Receptor 1 Antibody in Western Blot (WB)

图: 1 / 1

Cannabinoid Receptor 1 Antibody (PA5-142758) in WB

Western Blot analysis of Cannabinoid Receptor 1 in Rat Brain lysate (35 µg protein in RIPA buffer) using Cannabinoid Receptor 1 Polyclonal Antibody (Product # PA5-142758) at 0.3 µg/mL incubated for 1 hour. Detected by chemiluminescence.

Cannabinoid Receptor 1 Antibody in Western Blot (WB)

Product Image Gallery

Cannabinoid Receptor 1 Antibody in Western Blot (WB) — Western Blot analysis of Cannabinoid Receptor 1 in Rat Brain lysate (35 µg protein in RIPA buffer) using Cannabinoid Receptor 1 Polyclonal Antibody (Product # PA5-142758) at 0.3 µg/mL incubated for 1 hour. Detected by chemiluminescence.

产品信息

PA5-142758

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-3 µg/mL

-

产品规格

种属反应

Rat

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide with sequence C-NITEFYNKSLSSFKE.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2933404

产品详细信息

Additional Information: This antibody is expected to recognize both reported isoforms (NP_057167.2; NP_149421.2).

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

靶标信息

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Brain-type cannabinoid receptor; Cannabinoid receptor 1; CB-R; CB1; CB1 receptor; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1

查看更多收起

基因别名: Cnr1; Skr6; SKR6R

查看更多收起

UniProt ID: (Rat) P20272

查看更多收起

Entrez Gene ID: (Rat) 25248

查看更多收起

cannabinoid receptor activity protein binding drug binding G-protein coupled receptor

参与通路

positive regulation of acute inflammatory response to antigenic stimulus G-protein coupled receptor signaling pathway adenylate cyclase-modulating G-protein coupled receptor signaling pathway spermatogenesis axonal fasciculation aging response to nutrient learning or memory memory positive regulation of neuron projection development regulation of lipid metabolic process sensory perception of pain positive regulation of fever generation negative regulation of fatty acid beta-oxidation regulation of synaptic transmission, GABAergic response to lipopolysaccharide negative regulation of mast cell activation negative regulation of dopamine secretion response to nicotine cannabinoid signaling pathway response to cocaine glucose homeostasis positive regulation of apoptotic process negative regulation of ion transport response to morphine response to ethanol negative regulation of action potential negative regulation of blood pressure positive regulation of blood pressure regulation of insulin secretion negative regulation of nitric-oxide synthase activity regulation of synaptic transmission, glutamatergic maternal process involved in female pregnancy regulation of feeding behavior regulation of penile erection