Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Cannabinoid Receptor 1 Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 3
Cannabinoid Receptor 1 Antibody (PA5-18427) in WB
Western blot was performed using Anti-Cannabinoid Receptor 1 Antibody, (Product # PA5-18427) and a 53 kDa band corresponding to Cannabinoid Receptor 1 was observed across tissues except in Mouse Heart, Mouse Liver, Rat Heart and in Rat Liver which are reported to be negative. Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Mouse Cerebellum (Lane 2), Mouse Pup Brain (Lane 3), Rat Brain (Lane 4), Rat ... View More
产品信息
PA5-18427
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (HTSEDGKVQVTRPDQ) corresponding to the internal amino acids of CNR1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10982519
产品详细信息
This antibody is predicted to react with canine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB-R; CB1 receptor; central cannabinoid receptor; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1
基因别名: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; CNR1
UniProt ID: (Human) P21554
Entrez Gene ID: (Human) 1268
positive regulation of acute inflammatory response to antigenic stimulus
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
spermatogenesis
axonal fasciculation
aging
response to nutrient
memory
positive regulation of neuron projection development
sensory perception of pain
positive regulation of fever generation
negative regulation of fatty acid beta-oxidation
regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
negative regulation of mast cell activation
negative regulation of dopamine secretion
response to nicotine
cannabinoid signaling pathway
response to cocaine
glucose homeostasis
positive regulation of apoptotic process
negative regulation of ion transport
response to morphine
response to ethanol
negative regulation of action potential
negative regulation of blood pressure
positive regulation of blood pressure
regulation of insulin secretion
negative regulation of nitric-oxide synthase activity
regulation of synaptic transmission, glutamatergic
maternal process involved in female pregnancy
regulation of feeding behavior
regulation of penile erection
