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Carbonic Anhydrase IX Antibody (PA5-81331) in IHC (P)
Immunohistochemical staining of mouse Carbonic Anhydrase IX in mouse small intestine with Carbonic Anhydrase IX Polyclonal Antibody (Product # PA5-81331, 1:1,000 dilution, formalin-fixed paraffin embedded sections).
产品信息
PA5-81331
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Mouse Carbonic Anhydrase IX/CA9 Protein (Met1-Asp390)
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7
内含物
0.03% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2788547
产品详细信息
This antibody has specificity for Mouse Carbonic Anhydrase IX/CA9.
靶标信息
Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CA-9; CA-IX; Carbonate dehydratase IX; Carbonic anhydrase 9; Carbonic anhydrase IX; Membrane antigen MN homolog; P54 / 58N
基因别名: Ca9; CAIX; Car9; MN/CA9
UniProt ID: (Mouse) Q8VHB5
Entrez Gene ID: (Mouse) 230099
