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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cat K; Cathepsin K; Cathepsin O; cathepsin O1; Cathepsin O2; Cathepsin X; MGC23107; minisatellite 10q detected by probe MMS10
基因别名: AI323530; catK; CTS02; CTSK; CTSO; CTSO1; CTSO2; MMS10-Q; Ms10q; PKND; PYCD
UniProt ID: (Human) P43235, (Rat) O35186, (Mouse) P55097
Entrez Gene ID: (Human) 1513, (Rat) 29175, (Mouse) 13038
分子生物学功能:
cysteine protease