Invitrogen

Cdc42EP2 Polyclonal Antibody

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Cdc42EP2 Antibody (PA5-36579) in WB

Western blot analysis of Cdc42EP2 in Lane 1: HeLa cell lysate, Lane 2: mouse kidney tissue lysate, Lane 3: rat liver tissue lysate. Samples were incubated with Cdc42EP2 polyclonal antibody (Product # PA5-36579) at a dilution of 1:500.

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产品信息

PA5-36579

应用

建议稀释比

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免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to amino acids 1-50 of human Cdc42EP2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2553596

产品详细信息

This antibody detects endogenous protein at a molecular weight of 23 kDa.

Purity is >95% by SDS-PAGE.

靶标信息

Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.

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