Invitrogen

Cdc42EP2 Polyclonal Antibody

Cdc42EP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Cdc42EP2 Antibody (PA5-58441) in IHC (P)

Immunohistochemical analysis of Cdc42EP2 in human stomach using Cdc42EP2 Polyclonal Antibody (Product # PA5-58441) shows string cytoplasmic and membrane positivity in glandular cells.

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产品信息

PA5-58441

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human Cdc42EP2. Recombinant protein control fragment (Product #RP-97382).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2639564

产品详细信息

Immunogen sequence: PRLHLETPQP SPQEGGSVDI WRIPETGSPN SGLTPESGAE EPFLSNASSL LSLHVDLGPS ILDDVLQIMD QDLDSMQI

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 76%.

靶标信息

Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.

仅用于科研。不用于诊断过程。未经明确授权不得转售。