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Chitotriosidase Antibody (PA5-82395) in IHC (P)
Immunohistochemical analysis of Chitotriosidase in human bone marrow using Chitotriosidase Polyclonal Antibody (Product # PA5-82395) shows moderate cytoplasmic positivity in hematopoietic cells.
产品信息
PA5-82395
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2789554
产品详细信息
Immunogen sequence: FDDVESFKTK VSYLKQKGLG GAMVWALDLD DFAGFSCNQG RYPLIQTLRQ ELSLPYLPSG TPELEVPKPG QPSEPEHGPS PGQDTFCQGK ADGLYPNPRE RSSFYSCAAG RLFQQSCPTG LVFSNSCKCC TWN
靶标信息
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chitinase 1 (chitotriosidase); Chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
基因别名: CHI3; CHIT; CHIT1; CHITD
UniProt ID: (Human) Q13231
Entrez Gene ID: (Human) 1118
