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产品信息
MA5-24132
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
397504
抗原
Mouse myeloma cell line NS0-derived recombinant human Chitotriosidase/CHIT1 Ala22-Asn466
偶联物
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2607953
产品详细信息
In direct ELISAs, no cross-reactivity with recombinant human CHI3L1 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chitinase 1 (chitotriosidase); Chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
基因别名: CHI3; CHIT; CHIT1; CHITD
UniProt ID: (Human) Q13231
Entrez Gene ID: (Human) 1118
