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Chromogranin A Precursor Antibody (PA5-18527) in IHC (P)
Immunohistochemistry analysis of Chromogranin A Precursor in human small intestine. Samples were incubated with Chromogranin A Precursor polyclonal antibody (Product # PA5-18527) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
产品信息
PA5-18527
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (QGAKERAHQQKKH) corresponding to the internal amino acids of CHGA (aa 85-98).
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10979657
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
靶标信息
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; chromofungin; Chromogranin-A; Parastatin; parathyroid secretory protein 1; Pituitary secretory protein I; SP-I; SP1; Vasostatin
基因别名: CGA; CHGA
UniProt ID: (Human) Q9BQB5
Entrez Gene ID: (Human) 1113
regulation of the force of heart contraction
mast cell chemotaxis
organelle organization
regulation of blood pressure
positive regulation of cAMP metabolic process
killing of cells of other organism
mast cell cytokine production
negative regulation of catecholamine secretion
ovulation cycle
mast cell degranulation
innate immune response
mast cell activation
negative regulation of vasodilation
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
defense response to fungus
positive regulation of cardiac muscle contraction
adrenergic receptor signaling pathway involved in cardiac muscle relaxation
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
negative regulation of neuron death
positive regulation of relaxation of cardiac muscle
positive regulation of dense core granule biogenesis
