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CoCoA Antibody (A300-818A) in WB
Detection of human and mouse CoCoA by WB (h&m) and immunoprecipitation (h). Samples: Whole cell lysate from HeLa (H; 50 µg), 293T (T; 50 µg), NIH3T3 (N; 50 µg), Ramos (R; 50µg), and MCF7 (M; 50 µg for WB; 1 mg for IP, 20% of IP loaded) cells. Antibodies: Affinity purified rabbit anti-CoCoA antibody BL2456 (Cat. No. A300-818A) used for WB at 0.4 µg/ml (A) and 1 µg/ml (B) and used for IP at 3 µg/mg lysate (B). CoCoA was also immunoprecipitated by rabbit anti-CoCoA antibody BL2455 (Cat. No. A300-817A), which recognizes an... View More
产品信息
A300-818A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 650 and the C-terminus (residue 691) of human Coiled-Coil Transcriptional Coactivator 1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat and Orangutan
靶标信息
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/beta-catenin signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium-binding and coiled-coil domain-containing protein 1; Calphoglin; Coiled-coil coactivator protein; coiled-coil leucine zipper coactivator 1; coiled-coil transcriptional coactivator; granule cell antiserum positive 11; GRIP1-interacting protein; inorganic pyrophosphatase activator; Sarcoma antigen NY-SAR-3
基因别名: 1810009B06Rik; CALCOCO1; calphoglin; CocoA; Gcap11; KIAA1536; mKIAA1536; PP13275; UNQ2436/PRO4996
UniProt ID: (Human) Q9P1Z2, (Mouse) Q8CGU1
Entrez Gene ID: (Human) 57658, (Mouse) 67488
core promoter binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
protein binding
beta-catenin binding
protein C-terminus binding
ligand-dependent nuclear receptor transcription coactivator activity
sequence-specific DNA binding
transcription regulatory region DNA binding
armadillo repeat domain binding
transcription, DNA-templated
signal transduction
positive regulation of gene expression
Wnt signaling pathway
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of nucleic acid-templated transcription
