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Antibody detects endogenous levels of total Collagen V alpha 1.
COL5A1 encodes an alpha chain for one of the lowabundance fibrillar collagens. Fibrillar collagen molecules aretrimers that can be composed of one or more types of alpha chains.Type V collagen is found in tissues containing type I collagen andappears to regulate the assembly of heterotypic fibers composed ofboth type I and type V collagen. COL5A1 product is closelyrelated to type XI collagen and it is possible that the collagenchains of types V and XI constitute a single collagen type withtissue-specific chain combinations. Mutations in this gene areassociated with Ehlers-Danlos syndrome, types I and II.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AB collagen; COL5; Collagen 5; Collagen alpha-1(V) chain; collagen, type V, alpha 1; RP11-263F14.1; Type V Collagen
基因别名: COL5A1; EDSC
UniProt ID: (Human) P20908
Entrez Gene ID: (Human) 1289