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产品信息
MA1-26150
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
MC5-HA
抗原
Purified, full length, native human protein.
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
IgM
保存液
0.01M sodium borate/PBS, pH 8, with 1% dextran, 1% mannitol
内含物
no preservative
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_779886
产品详细信息
MA1-26150 detects Collagen V from human samples.
靶标信息
COL5A1 encodes an alpha chain for one of the lowabundance fibrillar collagens. Fibrillar collagen molecules aretrimers that can be composed of one or more types of alpha chains.Type V collagen is found in tissues containing type I collagen andappears to regulate the assembly of heterotypic fibers composed ofboth type I and type V collagen. COL5A1 product is closelyrelated to type XI collagen and it is possible that the collagenchains of types V and XI constitute a single collagen type withtissue-specific chain combinations. Mutations in this gene areassociated with Ehlers-Danlos syndrome, types I and II.
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生物信息学
蛋白别名: AB collagen; COL5; Collagen 5; Collagen alpha-1(V) chain; collagen, type V, alpha 1; RP11-263F14.1; Type V Collagen
基因别名: COL5A1; EDSC
UniProt ID: (Human) P20908
Entrez Gene ID: (Human) 1289
blood vessel development
heart morphogenesis
cell adhesion
cell migration
extracellular matrix organization
collagen fibril organization
collagen catabolic process
collagen biosynthetic process
wound healing, spreading of epidermal cells
tendon development
extracellular fibril organization
skin development
integrin biosynthetic process
eye morphogenesis
regulation of cellular component organization
negative regulation of endodermal cell differentiation
