Invitrogen

Connexin 37 Polyclonal Antibody

Connexin 37 Antibody in Immunohistochemistry (IHC)

图: 1 / 5

Connexin 37 Antibody (40-4200) in IHC

Indirect immunofluorescent analysis of blood vessels of (A) mouse uterus and (B) mouse lung using Zymed Rb anti-Connexin 37 (C-term) (Product # 40-4300). Image courtesy of James I. Nagy, PhD, University of Manitoba, Canada.

Connexin 37 Antibody in Western Blot (WB)

Connexin 37 Antibody in Immunohistochemistry (Frozen) (IHC (F))

Product Image Gallery

产品信息

40-4200

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-3 µg/mL

查看2篇已发表文章 2篇已发表文章

免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（冰冻） (IHC (F))

Assay-dependent

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Mouse

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide derived from the C-terminal region of the mouse connexin 37 protein

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.1% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2533464

产品详细信息

40-4200 was used in the immunofluorescence (IHC) analysis to successfully detect Connexin 37 in mouse heart sections.

靶标信息

This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac.

Development (Cambridge, England)

Li-Villarreal N,Wong RLY,Garcia MD,Udan RS,Poché RA,Rasmussen TL,Rhyner AM,Wythe JD,Dickinson ME

40-4200 was used in Immunohistochemistry-immunofluorescence to demonstrate that at E8.25, loss of Foxo1 in Tie2-cre expressing cells resulted in increased sprouty 2 (Spry2) and Spry4 expression, reduced arterial gene expression and reduced Kdr transcripts without affecting overall endothelial cell identity, survival or proliferation.

Fri Apr 01 00:00:00 EDT 2022

GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126.

Development (Cambridge, England)

Mahamud MR,Geng X,Ho YC,Cha B,Kim Y,Ma J,Chen L,Myers G,Camper S,Mustacich D,Witte M,Choi D,Hong YK,Chen H,Varshney G,Engel JD,Wang S,Kim TH,Lim KC,Srinivasan RS

40-4200 was used in Immunohistochemistry to define a new mechanism of GATA2 activity and uncover miR-126 as a novel regulator of mammalian lymphatic vascular development.

Tue Nov 05 00:00:00 EST 2019

Lymph flow regulates collecting lymphatic vessel maturation in vivo.

The Journal of clinical investigation

Sweet DT,Jiménez JM,Chang J,Hess PR,Mericko-Ishizuka P,Fu J,Xia L,Davies PF,Kahn ML

Published figure using Connexin 37 polyclonal antibody (Product # 40-4200) in Western Blot

Mon Aug 03 00:00:00 EDT 2015

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax.

Developmental biology

Kanady JD,Dellinger MT,Munger SJ,Witte MH,Simon AM

40-4200 was used in Immunohistochemistry to show that at least three Cxs are expressed in the developing lymphatic vasculature and, when defective, are associated with clinically manifest lymphatic disorders in mice and man.