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Bethyl Laboratories

Cul1 Polyclonal Antibody

查看其他9个Cullin 1抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (2)

Application

Cul1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

Cul1 Antibody (A303-372A) in IHC (P)

Detection of human Cul1 by immunohistochemistry. Sample: FFPE section of human osteosarcoma. Antibody: Affinity purified rabbit anti-Cul1 (Product # A303-372A) (Lot 1) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB.

Cul1 Antibody in Immunoprecipitation (IP)

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产品信息

A303-372A

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化 (IHC)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:500-1:2,000

免疫沉淀 (IP)

2-10 µg/mg lysate

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Region between residue 250 and 300 of human Cullin 1.

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

tris citrate/phosphate, pH 7-8

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

The recommended shelf life for this product is 1 year from date of receipt.

Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan

靶标信息

CUL1 gene ontology annotations related to this gene include animal organ morphogenesis; apoptotic process; cell proliferation; protein monoubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CUL-1; Cullin-1

基因别名: CUL1

UniProt ID: (Human) Q13616

Entrez Gene ID: (Human) 8454

功能

ubiquitin-protein transferase activity protein binding ubiquitin protein ligase binding ubiquitin protein ligase activity ubiquitin-protein ligase

参与通路

G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle protein polyubiquitination stimulatory C-type lectin receptor signaling pathway protein monoubiquitination cell cycle arrest cell proliferation negative regulation of cell proliferation organ morphogenesis viral process Wnt signaling pathway protein ubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process T cell receptor signaling pathway stress-activated MAPK cascade positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition intrinsic apoptotic signaling pathway