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Invitrogen
Cytochrome P450 Reductase Polyclonal Antibody, DyLight™ 488
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Cytochrome P450 Reductase Antibody (PA5-79849) in Flow
Flow Cytometry of Cytochrome P450 Reductase in A549 cells (blue line), isotype control rabbit IgG (green line) and unlabeled (red line). Samples were blocked with 10% goat serum and then incubated with Cytochrome P450 Reductase Polyclonal Antibody, DyLight™ 488 (Product # PA5-79849) at a dilution of 1 μg (per 1x10^6 cells) for 30 min at 20°C.
产品信息
PA5-79849
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human POR (633-668aa RNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTK).
偶联物
激发/发射光谱
492/519 nm
查看光谱
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746964
靶标信息
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
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生物信息学
蛋白别名: CCR; CPR; CY DKFZp686G04235; DKFZp686G04235; FLJ26468; NADPH Cytochrome; NADPH--cytochrome P450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450 Reductase
基因别名: CPR; CYPOR; P450R; POR
UniProt ID: (Human) P16435
Entrez Gene ID: (Human) 5447
NADPH-hemoprotein reductase activity
cytochrome-b5 reductase activity, acting on NAD(P)H
protein binding
nitric oxide dioxygenase activity
electron carrier activity
FMN binding
hydrolase activity
enzyme binding
[methionine synthase] reductase activity
iron-cytochrome-c reductase activity
flavin adenine dinucleotide binding
NADP binding
oxidoreductase
regulation of growth plate cartilage chondrocyte proliferation
xenobiotic metabolic process
response to nutrient
carnitine metabolic process
flavonoid metabolic process
internal peptidyl-lysine acetylation
fatty acid oxidation
positive regulation of chondrocyte differentiation
positive regulation of monooxygenase activity
response to drug
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
nitrate catabolic process
positive regulation of cholesterol biosynthetic process
positive regulation of smoothened signaling pathway
nitric oxide catabolic process
oxidation-reduction process
negative regulation of lipase activity
demethylation
cellular response to follicle-stimulating hormone stimulus
cellular response to peptide hormone stimulus
positive regulation of steroid hormone biosynthetic process
cellular organofluorine metabolic process
