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Invitrogen
Cytokeratin 7/17 Monoclonal Antibody (C-46)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
产品信息
MA1-19045
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Pig
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
C-46
抗原
Cytoskeleton preparation of HeLa human cervix carcinoma cell line.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1075188
产品详细信息
This antibody reacts with cytokeratin peptides 7 and 17 (54 and 46 kDa). Cytokeratins are members of intermediate filaments subfamily of intracellular proteins represented in epithelial tissues.
This antibody will not cross-react with mouse, rat or rabbit.
靶标信息
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 39.1; CK-17; CK-7; cytokeratin 7; Cytokeratin-17; Cytokeratin-7; K17; K7; keratin 17, type I; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type I cytoskeletal 17; Keratin, type II cytoskeletal 7; Keratin-17; Keratin-7; Sarcolectin; type II mesothelial keratin K7; Type-II keratin Kb7
基因别名: 39.1; CK-17; CK7; K17; K2C7; K7; KRT17; KRT7; PC; PC2; PCHC1; SCL
UniProt ID: (Human) Q04695, (Bovine) A1L595, (Bovine) Q29S21, (Human) P08729
Entrez Gene ID: (Human) 3872, (Bovine) 281889, (Bovine) 535697, (Human) 3855, (Pig) 100626483
