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Antibody detects endogenous levels of total DAO.
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AOC1; D-amino acid oxidase 1; D-amino-acid oxidase; DAAO; DAMOX
基因别名: AI987963; DAAO; DAMOX; DAO; Dao-1; Dao1; OXDA
UniProt ID: (Human) P14920, (Rat) O35078, (Mouse) P18894
Entrez Gene ID: (Human) 1610, (Rat) 114027, (Mouse) 13142