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产品信息
H00023604-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3D4
抗原
DAPK2 (AAC35001, 281 a.a. approximately 370 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: RHPWITPVDN QQAMVRRESV VNLENFRKQY VRRRWKLSFS IVSLCNHLTR SLMKKVHLRP DEDLRNCESD TEEDIARRKA LHPRRRSSTS
靶标信息
DAPK2 is a calcium/calmodulin-dependent kinase that acts as a positive regulator of apoptosis, and is expressed in many tissue types. DAPK2 encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DAP kinase 2; DAP-kinase-related protein 1; DAP-kinase-related protein 1 beta isoform; Death-associated protein kinase 2; DRAK2; DRP-1; MGC119312
基因别名: DAPK2; DRP-1; DRP1
UniProt ID: (Human) Q9UIK4
Entrez Gene ID: (Human) 23604
protein phosphorylation
apoptotic process
regulation of autophagy
intracellular signal transduction
regulation of apoptotic process
anoikis
protein autophosphorylation
positive regulation of neutrophil chemotaxis
neutrophil migration
positive regulation of eosinophil chemotaxis
regulation of intrinsic apoptotic signaling pathway
