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Immunogen sequence: SSPRWRENSP EPSERLIQES SGAPPPEANS LQGALYLCSE EEAGSKGVLT G
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 53%.
DBX2 is a member of the developing brain homeobox (DBX) protein family, but while the related protein DBX1 is expressed in various regions of the developing brain, DBX2 shows a more restricted pattern of expression in the brain, and is also expressed in some mesenchymal cells such as limb buds and tooth germs. It is thought that DBX1 and DBX2 promote the development of a subset of interneurons, some of which help mediate left-right coordination of locomotor activity. In Xenopus, DBX2 is involved in primary neurogenesis and early neural plate patterning, and is thought to act as a cross-repressive partner of NKX6-2 in the patterning of the ventral neural tube.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Developing brain homeobox protein 2; Homeobox protein DBX2
基因别名: DBX2
UniProt ID: (Human) Q6ZNG2
Entrez Gene ID: (Human) 440097