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For Western Blot, this antibody has non-specific bands at 14 kDa,70 kDa and 78 kDa.
This antibody is predicted to react with mouse, rat and dog based on sequence homology.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DEAD (Asp-Glu-Ala-Asp) box helicase 17; DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; DEAD box protein 17; DEAD box protein p72; DEAD box protein p82; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD); DEAD/H box 17; DKFZp761H2016; Probable ATP-dependent RNA helicase DDX17; RNA-dependent helicase p72; RP3-434P1.1
基因别名: DDX17; P72; RH70
UniProt ID: (Human) Q92841
Entrez Gene ID: (Human) 10521