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产品信息
MA5-45960
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3E8
抗原
Full Length Human Recombinant Dennd4c protein
偶联物
激发/发射光谱
651/660 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
95.64mM phosphate/2.48mM MES, pH 7.4, with 0.5M EDTA
内含物
no preservative
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2932414
产品详细信息
A 1:1,000 dilution of MA5-45960 was sufficient for detection of DENND4C in A549, MEF cells by Western Blot analysis.|Detects approximately 213 kDa.
靶标信息
DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DENN domain-containing protein 4C; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C; likely ortholog of H. sapiens chromosome 9 open reading frame 55 (C9orf55)
基因别名: 1700065A05Rik; AA420392; bA513M16.3; C9orf55; C9orf55B; DENND4C; RAB10GEF; RGD1308489
UniProt ID: (Human) Q5VZ89, (Mouse) A6H8H2
Entrez Gene ID: (Human) 55667, (Mouse) 329877, (Rat) 313340
